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| Slot Name | Value | |
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Alternatives | |
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CanImprove | |
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CautionWithMedicationsUsed | |
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Comment | |
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Contraindication | |
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CouldBeRelatedTo | |
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Cui | C0054836 |
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Definition | A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. (NCI04) |
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DespiteReceivingTreatment | |
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DoNotUseWithMedicationGroup | |
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EspeciallyEffectiveAgainst | |
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Improves | |
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Incrementsmgday | 6.25, 12.5, 25, 50 |
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InitiatingDose | 3.125 mg b.i.d. |
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MaintenanceDose | |
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MaximumRecommendedDailyDose | |
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MeanDailyDose | |
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RelevantSignOrSymptom | |
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SideEffect | |
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Synonyms | |
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TargetDose | 25-50 mg b.i.d. |
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TitrationPeriod | 2-4 weeks |
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TreatmentStatus | |
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Treats | |
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UMLSSynonyms | |
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UsedTogetherWithMedication | |
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UsedWithMedicationGroup | |
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UseWhenExistsIntoleranceOf | |
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UseWithTest |