Instance: Milrinone
Types
Inotropic_agent
Own Slots
Slot Name
Value
Alternatives
CanImprove
Increased_pulmonar_capillary_wedge_pressure
,
Acute_myocardial_ischemia
,
Chronic_ischemic_heart_disease
CautionWithMedicationsUsed
Comment
Contraindication
CouldBeRelatedTo
Cui
C0128513
Definition
A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the ionotropic potency of amrinone.
DespiteReceivingTreatment
DoNotUseWithMedicationGroup
EspeciallyEffectiveAgainst
Improves
Incrementsmgday
InitiatingDose
MaintenanceDose
(infusion) 0.375-0.75 ug/kg/min
MaximumRecommendedDailyDose
MeanDailyDose
RelevantSignOrSymptom
SideEffect
Atrial_fibrillation
,
Systolic_hypotension
,
Any_arrhythmia
,
Diastolic_hypotension
Synonyms
TargetDose
(bolus): 25-75 ug/kg over 10-20 min
TitrationPeriod
TreatmentStatus
Treats
UMLSSynonyms
UsedTogetherWithMedication
UsedWithMedicationGroup
Adrenergic_beta-antagonists
UseWhenExistsIntoleranceOf
UseWithTest
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Generated: 09/08/2009, 5:06:54 PM, Central European Summer Time
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