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Own Slots | ||
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Slot Name | Value | |
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Alternatives | |
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CanImprove | |
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CautionWithMedicationsUsed | |
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Contraindication | |
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CouldBeRelatedTo | |
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Cui | C0041041 |
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Definition | A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported. (MeSH) |
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UMLSSynonyms | |
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UsedTogetherWithMedication |