| Own Slots |
| |
Slot Name |
Value |
 |
Alternatives |
Angiotensin_II_receptor_blockers |
|
CanImprove |
|
|
CautionWithMedicationsUsed |
|
|
Comment |
|
|
Contraindication |
History_of_angioedema, Bilateral_renal_artery_stenosis, Severe_aortic_stenosis, Hyperkalemia, Increased_creatinine |
|
CouldBeRelatedTo |
Systolic_hypertension, Acute_myocardial_infarction, Reduced_left_ventricular_ejection_fraction, Diastolic_hypertension |
|
Cui |
C0003015 |
|
Definition |
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility. |
|
DespiteReceivingTreatment |
|
|
DoNotUseWithMedicationGroup |
Potassium_sparing_diuretics |
|
EspeciallyEffectiveAgainst |
High_serum_creatinine_or_BUN |
|
Improves |
Mortality |
|
Incrementsmgday |
|
|
InitiatingDose |
|
|
MaintenanceDose |
|
|
MaximumRecommendedDailyDose |
|
|
MeanDailyDose |
|
|
RelevantSignOrSymptom |
|
|
SideEffect |
Hyperkalemia, Renal_insufficiency, Carotid_sinus_syncope, Low_blood_pressure_disorder, Coughing |
|
Synonyms |
|
|
TargetDose |
|
|
TitrationPeriod |
|
|
TreatmentStatus |
|
|
Treats |
|
|
UMLSSynonyms |
Angiotensin-converting_enzyme_inhibitor_agent |
|
UsedTogetherWithMedication |
|
|
UsedWithMedicationGroup |
Loop_diuretics_and_metolazone, Aldosterone_receptor_antagonists |
|
UseWhenExistsIntoleranceOf |
|
|
UseWithTest |
Complete_blood_count, Serum_urea, Serum_urate |
